Comprehensive Oral Test

Get a complete picture of your health, not just your mouth. Take the DNA ConneXions Comprehensive Oral Test at home or in your practitioner’s office.

Are you searching for answers about your oral health or health in general?

You’ve done what you’re “supposed” to do—brushed, flossed, rinsed. Yet you still have:

• Bad breath that won’t go away
• Bleeding gums or gum recession
• A metallic taste or constant dry mouth
• Unexplained inflammation, fatigue, or chronic illness

And every time, you’re told: “Everything looks normal.”

You’re not overreacting. It’s not “all in your head.” You’re just not being shown the whole picture.

Your oral flora plays a critical role in maintaining both oral and systemic health, and imbalances are linked to chronic conditions such as cardiovascular disease, diabetes, and autoimmune disorders. The DNA ConneXions Comprehensive Oral Test identifies the DNA of 88 potentially harmful microbes that could be residing in your mouth. This test provides early warning signs of disease, identifies bacterial and viral risks, and helps guide targeted, personalized treatment strategies.

What This Test Reveals About Your Whole-Body Health

The Oral-Gut Connection

Research confirms that your oral microbiome has a direct impact on your gut. Harmful mouth bacteria don’t stay put; they’re swallowed with saliva thousands of times a day, seeding inflammation and imbalance throughout your digestive tract and body.

“Oral health is connected to full-body health in myriad ways. In fact, conditions ranging from obesity, diabetes, cardiovascular disease, rheumatoid arthritis, inflammatory bowel disease, and even dementia are all directly connected to poor oral health.” —Dr. Todd LePine, MD IFMCF

 

Why Take the DNA ConneXions Comprehensive Oral Test?

• 88 Microbes Identified
  We detect bacteria, viruses, parasites and fungi.
• Lab-Accuracy from Home
  Although your Dentist or practitioner can do this test for you, we make it easy to do yourself at home. Collect your sample painlessly with a specialized floss or saliva kit—no appointment, no blood, no guesswork.
• Uncover the Underlying Cause
  Investigates your oral flora, the unique ecosystem of microbes in your mouth, to uncover imbalances of 88 known potential pathogens.
• Used by Holistic & Functional Medicine Doctors, & Biological Dentists
  Join the numerous patients and practitioners around the world who use this test to support root-cause healing.

 

Pathogens We Detect and Why They Matter

Your mouth hosts hundreds of microbial species, but when this ecosystem becomes unbalanced, pathogens can trigger oral and systemic disease. Below are just a few of the 88 species we test for and what they can indicate:

• Acinetobacter baumannii – Linked to respiratory infections and drug-resistant pneumonia
• Cytomegalovirus (CMV) – A herpesvirus that can weaken immunity and inflame tissues
• Klebsiella pneumoniae – Associated with periodontal disease and systemic infections
• Rothia dentocariosa – Contributes to dental caries and endocarditis (heart inflammation)
• HPV 16 / HPV 18 / HPV 58 – High-risk strains linked to oral, throat, and cervical cancers
• Granulicatella adiacens – Found in cases of bacterial endocarditis and bloodstream infections
• Propionibacterium acnes – Associated with implant failure and jawbone infections
• Veillonella parvula – Plays a role in periodontal disease and chronic inflammation
• Enterobacter aerogenes – A gut-associated bacterium that may indicate microbial imbalance
• Gemella morbillorum – Associated with dental abscesses and heart infections
• Entamoeba species – Oral protozoa linked to periodontal breakdown and digestive distress
• Eikenella corrodens – A frequent contributor to gum infections and oral abscesses
• Blastomyces dermatitidis – A fungus that can affect the lungs and sometimes the mouth
• Actinomyces species (gerencseriae, naeslundii, israelii) – Implicated in dental root infections, gum inflammation, and even actinomycosis (chronic tissue infection)
• Campylobacter and Helicobacter species – Often associated with gut inflammation and ulcers but can start in the mouth
• Candida albicans – A yeast responsible for oral thrush, immune issues, and gut imbalance

 

Why The DNA ConneXions Comprehensive Oral Test Is Better Than Others

The DNA ConneXions Comprehensive oral test is better than others because:

1. DNA Precision for 88 Pathogens

Most at-home oral tests focus on general microbiome balance or just a handful of bacteria.
DNA ConneXions offers the largest available test, utilizing PCR (polymerase chain reaction) technology to detect the presence of 88 known pathogens—including bacteria, viruses, parasites and fungi.

This means you get targeted, actionable information instead of vague microbiome scores or gut-health buzzwords.

2. Not Just Bacteria—Also Viruses, Parasites and Fungi

Competing tests often miss major players like:

• HPV high risk types linked to oral and cervical cancer
• Candida albicans linked to thrush and systemic fungal infections
• Entamoeba species (oral protozoa)
• Cytomegalovirus (CMV) and Blastomyces dermatitidis

This test looks beyond gum disease to identify real threats to your immune system and whole-body health.

3. Developed for Practitioners-Available to You

Holistic, functional, and integrative doctors, and biological dentists worldwide use this test to guide real treatment decisions.

Now, you can access the same diagnostic tools without needing a provider referral.

4. Easy, Non-Invasive Sample Collection

No blood, no swabs stuck deep in your throat, just a sterile floss or saliva collection kit done at home in 5 minutes. Or, if you are working with your dentist, the dentist can also choose to collect the following sample types for testing: oral bone, cavitations, extracted dental implants, teeth, and root canaled teeth, oral blood, paper points or oral tissue. Just be sure to order the correct sample type when ordering.

5. Results You Can Use

Forget vague pie charts. You’ll receive a detailed, easy-to-read report showing which of the 88 microbes were detected, a general description of each organism, possible symptoms of infection and CDC recommended treatment options. Share this with your practitioner to start your healing journey.

6. Connects Oral Health to Whole-Body Health

Most tests stop at the gums. This test helps uncover microbial links between oral pathogens and whole-body issues like:

• Gut dysbiosis and IBD
• Autoimmune flare-ups
• Cardiovascular inflammation
• Cognitive decline (Alzheimer’s)
• Long-term fatigue and chronic illness

 

It’s not just about your mouth, it’s about your whole life.

Real Stories. Real Results.

“After years of mystery symptoms and no help from my dentist, this test gave me the answers I needed. The report showed pathogens my dentist never mentioned—and now I’m on a real path to healing.”
— Leah M., Ohio

“It wasn’t just about my mouth. Once I treated the oral bacteria, my gut and skin issues started improving too.”
— James D., California

 

Frequently Asked Questions (FAQ’s)

Do I need to stop brushing, flossing or rinsing before the sample collection?
Yes. For best results, collect your sample first thing in the morning before brushing, eating, or drinking.

Can this test replace a dental visit?
This test cannot replace a dental visit. Dental visits are important for identifying tooth decay. Our test will give you insight into which organisms could be causing the symptoms you are experiencing.

How are the microbes detected?
We use polymerase chain reaction (PCR) technology to detect the DNA of 88 pathogens, even in low concentrations.

Can I take this test if I have gum disease or implants?
Absolutely. In fact, the test is especially valuable for people with chronic oral issues, implants, gum disease and/or autoimmune symptoms.

What are the Available Sampling Methods?

At home sampling methods are quick and easy and include:

• Saliva
• Super Floss

Dental office sampling methods include:                                               

• Bone
• Cavitations
• Dental Implants
• Extracted Teeth
• Oral Blood
• Paper Points
• Root Canals
• Saliva
• Super Floss
• Tissue

Comprehensive Collection Kits: The provided collection kits include everything needed to collect, package, and return samples to DNA ConneXions.

Please Note: If you select combination testing, both samples need to be returned together.

How soon will I get results?
Results are delivered electronically within 7-10 Business Days after we receive your sample.

Take the First Step Toward Full-Body Wellness

You’ve felt the symptoms. You’ve asked for answers.
Now you can get them, on your terms.

The DNA ConneXions Comprehensive Oral Test empowers you to take charge of your oral and systemic health from home.