DNA Connexions is a CLIA certified clinical molecular laboratory specializing in the detection and identification of the genetic footprint of pathogenic microbiota.
We also look for specific genetic variations that would give our clients a better understanding of their ability to handle the environment they live in.
The company mission of DNA Connexions is to conduct targeted genetic testing to identify both inherited conditions and the presence of foreign DNA; to provide healthcare professionals with information necessary for accurate diagnosis and eventual treatment; and, to pursue targeted research to develop and refine testing methods that ever more fully satisfy our clients’ needs.
Currently, DNA Connexions offers four molecular-based laboratory assays: the Lyme Detection Panel, the Fullview (i.e., comprehensive oral heath) Panel, the Apolipoprotein E (ApoE) Panel, and the Gluten Intolerance Panel. For more informaation, please see Tests Provided.
An assay is an essentially investigative procedure used either to qualitatively assess or to quantitatively measure some target entity usually according to its presence, amount, or functional activity. Accordingly, an assay is generally a direct form of testing.
A test is ‘direct’ when it seeks to detect the presence of the organism suspected as the cause of an infection. Conversely, a test is said to be ‘indirect’ when it’s focus is on the immune response of the person who provided the sample for testing.
The Lyme detection panel is a urine-based PCR (i.e., polymerase chain reaction) assay designed to detect the genetic footprint of Borrelia burgdorferi, the most common cause of Lyme infection in the United States, as well as the footprints of ten common Lyme co-infectors.
No, a positive test result does not mean the tested patient has Lyme disease. Rather, it means the DNA footprint of B. burgdorferi was detected in the sample provided. For a diagnosis or interpretation of your results, please consult your primary care or Lyme-literate physician.
This is very possible. At any given time, we literally have millions of pathogenic microorganisms (bacteria, viruses, parasites, and fungi) living within us, and the immune system is constantly fighting them. Therefore, their mere presence does not make us sick.
Lyme disease, like all other microbial infections, requires an already compromised immune system in its host.
Certainly! A ‘pathogen’ is a harmful foreign organism within the body. The ‘immune system’ is the body’s self defense mechanism. If the immune system is strong, then the pathogen will eventually be completely destroyed. However, if the immune system is compromised by poor health, the pathogen multiplies, becoming an ‘infector,’ and the resultant immune response to this pathogenic aggression is an ‘infection.’ So, applying these terms to the Lyme discussion: a) Borrelia burgdorferi is a either a temporarily co-existing pathogen or an active infector; b) Borreliosis (i.e., Lyme Disease) is an infection. The same distinction applies to the ‘co-infectors’ our panel is designed to detect. They are ‘co-infectors,’ not ‘co-infections.’ We know this can get confusing at times, but it’s vital to keep our words, and the ideas behind them, clear.
We do not advise clients regarding either the continuation or cessation of treatments prior to taking any of our tests. That is the responsibility of their physician. Some of our clients have highly individualized medical situations, which may or may not include treatment for Lyme Disease. We recommend that you consult your primary care or Lyme-literate physician for advice about any medications or other treatments you may be taking, and prior to taking our test.
The causes of infection are pathogens – whether viral, bacterial, parasitic, or fungal – and a weakened immune system.
No, DNA Connexions does not specialize in Lyme detection. In fact, the laboratory offers three other tests for its clients: the Fullview Panel, the ApoE Panel, and the Gluten Intolerance Panel.
The Full View test is an assay that identifies bacteria, viruses, fungi, and parasites using an oral sample. It tests for 88 different pathogens, including tetanus, botulism, diphtheria, HPV 16 and HPV 18, and Candida albicans, to name but a few. For more information, please see Tests Provided.
Yes, and this is precisely why a dentist would be interested in helping medical doctors and other dentists make the differential diagnosis of mercury toxicity versus Lyme disease. Such common symptoms include: flu-like symptoms, low energy, headaches, panic attacks, swollen lymph nodes, joint pain, weakness, numbness and tingling, irregular heartbeat, tachycardia, poor memory, reduced mental focus, facial paralysis, depression, suicidal thoughts, cold sensitivity, dizziness, cognitive defects, sleep disturbance, elevated liver enzymes, other autoimmune problems, and awkward gait.
Polymerase chain reaction (PCR) is a molecular biological tool used to make many copies of a specific sequence of DNA.
PCR testing enables us to look directly for the specific microbial DNA. Using this method, we can say for certain whether such microbes are present.
It is easier to collect urine than it is to draw blood. Also, urine is an excellent detection reservoir, since the urinary tract is known to be a place of spirochetal persistence (i.e., where spirochetes collect).
No, we do not offer either diagnoses or treatments in consequence of any of our tests, since we are simply a certified detection facility. If you require either a diagnosis or treatment, we encourage you to consult your primary care or Lyme-literate physician.