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Toll Free: 888-843-5832
Ph: 719-219-2826
Fax: 719-548-8220

APOE GENOTYPE

REVISED 06/11A

Apolipoprotein-E (ApoE) is composed of 299 amino acids and transports lipoproteins, fat-soluble vitamins, and cholesterol into the lymph system and then into the blood. It is synthesized principally in the liver, but has also been found in other tissues such as the brain, kidneys, and spleen. In the nervous system, non-neuronal cell types, most notably astroglia and microglia, are the primary producers of ApoE, while neurons preferentially express the ApoE receptors. There are seven currently identified mammalian receptors for ApoE which belong to the evolutionarily conserved low density lipoprotein receptor gene family.

People with harmful forms of the ApoE gene (genotype 3/4, 4/4) have up to 12 times the risk of developing Alzheimer's disease compared with those who have other variations (2/2, 2/3, 3/3) of the gene. Another role of ApoE is in the removal of mercury from the biosystem. The optimal genotype for removing mercury is ApoE 2/2 (4 cysteine residues),whereas ApoE 3/3 is the most prevalent in the human population (2 cysteine residues and 2 arginine residues), and the most detrimental is ApoE 4/4 (4 arginines and no mercury removing capability).

FULL FORMS REQUIRED FOR APOE GENOTYPE IN TESTING

Dropship Direct to Patient forms: (we are updating our forms - should be complete by June 7th)
Deposit Paid Saline Kits

Dropship Direct to Patient forms: (we are updating our forms - should be complete by June 7th)
Deposit Paid Blood Kits FedEx 08/15

LYME PANEL

The DNA Connexions Lyme Panel identifies 3 different Borrelia species and 8 of it’s common co-infectors. A positive PCR result indicates the presence of spirochete DNA, while negative result does not prove you don’t have Lyme disease

FULL VIEW

This test identifies foreign microbial DNA of aerobic and anaerobic bacteria, fungi, viruses and parasites in removed teeth, blood, tissue, implants, bone grafts and other biological samples. This test examines 88 microbes in total.

APOE GENOTYPING

Cheek cells allow us to determine your ability to detoxify mercury, Alzheimer's susceptibility and other autoimmune/ neurological diseases. This test will determine what ApoE genotype you are (2/2, 2/3, 3/3, 3/4, or 4/4)

GLUTEN INTOLERANCE

Cheek cells allow us to determine if you have the HLA marker for DQ 2 or DQ 8. The presence of either of these genetic markers is 95% predictive for gluten intolerance/sensitivity. The presence of both markers is 95% predictive

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